Swarupmay Majumdar Moderation hereby acknowledge all the guests at canine dermatolgy update that the event is now declared closed. we are planning to bring it alive same time next year.
we also plan to bring canine cardiology in next event
Sumit Virmani 35 days old Daschund male.
Patchy alopecia on back & ventral side, which is progressing, as per the owner.
No itching, no observable change in skin tone.
Swarupmay Majumdar Canine dermatology update is getting closed by tonite. Most members did not participate as they were not able to login. Most others were not able to do becoz they are peoccupied. How about extending the update for one more week? your feedback please.
Sumit Virmani Patchy alopecia with itching in a month old Daschund?
Most likely diagnosis ? Infection / allergy ?
Saurabh Saxena malassezia dermatits is almost always associated wid an underlying cause like atopy,food allergy,endocrinopathy,food allergy etc.for mild cases only topical therapy wid ketoconazole+chlorhexidine shampoo every 3 days is sufficient.i also use vinegar mixed in water to spray after every bath.. gives good results
Swarupmay Majumdar Bilaterallysymmetric lesions are typically
caused by internal disease such ashypothyroidism,
hyperadrenocorticism, or pemphigus foliaceus. Allergies mayalso
present with bilaterally symmetric symptom
Swarupmay Majumdar Localizedproblems may be due to infectious
organisms that gained entry at a certain siteand spread only locally
such as atypical mycobacterial or fungal infections. Neoplastic
disease is commonly localized, atleast initially. Generalized
disorders are more commonly dueto hypersensitivities or systemic
conditions such a...s endocrine disorders andimmune-mediated
or metabolic skin diseases.
Swarupmay Majumdar Some antibiotics, such astrimethoprim-sulfonamide
combinations, will affect blood concentrations ofthyroxin. Others
such as cephalosporins may affect the glucose readings of someurine
test strips.
Swarupmay Majumdar Incase of chronic Otitis externa the
differential diagnosis may include :Atopy, food adverse reaction,
parasites, polyps. Secondaryinfections are common and can also occur
with primary endocrine diseas like hypothyroidism
Swarupmay Majumdar If cutaneous signs
have been present for yearswithout the development of concurrent
systemic signs, endocrine disorders areunlikely.
Swarupmay Majumdar If pruritus was the first initial sign and
lesions occurredlater, then atopy or food-adverse reaction are most
likely. Pruritus withlesions that occur at approximately the same
time may be due to a wide varietyof causes
Swarupmay Majumdar Synthetic Levothyroxine at 0.02mg is the drug of choice for canine hypothyridism.
Swarupmay Majumdar Ketokonazole is also used in Canine Hyperadrenocorticism at 10mg/kg sid po once in 48 hrs. it may be required to be increases to 15mg/kg po sid 48hrly in case Cortisol level remains still above resting level.
Swarupmay Majumdar Ketokonazole works very well in acidic gastic environments. So H2 blockers or antacids are better not used simultaneously.
Swarupmay Majumdar Granulomatous Panuveitis, depigmentation hair and Skin ( vitiligo) are seen in a condition called VKH- vogt-Koyamagi Harad like syndrome. they are symmetrical and mostly on head region and appear acutely.
Swarupmay Majumdar in case of food allergy , commercial hypoallergenic diets are likely to be effective in 80% cases. The food brand change (usual from one to another) doesnot always reduce allergy and same food in future may also not cause allergy
Swarupmay Majumdar in any cases of Seborrhea corticosteroids are contraindicated for long time use as they can causedecrease in sebum production and increase scale productions
Gautam Unny When the skin does not heal and there is a recurrance of skin trouble, poor skin coat, hair loss at areas of friction, slow regrowth of hair, rat tailed appearence do think of the thyroid. also there seems to be a correlation between adult onset demodicosis and hypothyroidism. T3 has little significance in dogs. estima...
Swarupmay Majumdar I have found Immumod very effective in cases of reccurent pyoderma, abcess, digital abcess , and many other cases.( Thanks to Dr Gautam Unny for sharing this information on SAVIN)
Swarupmay Majumdar It is better to use immunostimulants or immuno modulators then using immuno supressants. I sometimes feel why everytime we chose a steroid for all skin problem! We need to search for immunomodualtors, immunostimulator and non sterods
Swarupmay Majumdar Ketokonazole is very effective even when used wkly 2 consecutive days for 4 wks instead of daily dosing. I mean sunday -monday.. wait .. sunday monday
Swarupmay Majumdar Methyl prednisolone( depromedrol) or Triamcelolone( vetlog) is not effective at all in any cases of atopy. But we still keep using them.
Swarupmay Majumdar Fatty acids as anti inflamatory agents in atopic dermatitis can help you in 20% cases.
But if employed with some antihistaminics they are working well
Swarupmay Majumdar Levamisole can be used thrice a week subcut for any bad cases of demodecosis. Levamisole works as an immunomodulator and can help
Swarupmay Majumdar Ketokonazole is know to be hepatotoxic, but toxicity is not so common. In any case it is better to use some liver protectant simmultaneously. It is also absorbed well when the food is rich in Fatty acid or fat.
Swarupmay Majumdar In severe cases of skin infections and abcess, Amoxycllin- clav is better used every 8 hrs. They actually work better when given thrice a day.
Swarupmay Majumdar Sometimes, you may find Amoxy-clav showing resistance in ABS, but still then you can continue using them sucessfully. So even though culture says Amoxy-clav may not work, but in real you can use it sucessfully.
Swarupmay Majumdar Clemastine can be very affective in controlling allergy in cats. It is not veryu effective in dogs and usually not used. It does not have tendency to cause drowsiness
Gautam Unny for scabies try psorinum 30 ( made from mites), for general poor skin use sulphur 200 once a week, for moist exzema use graphitis 30, for non healing skin lesions use ferrumphos 6x.
Surjit Singh Makker For maximum skin problems in dogs we use Acid Flour200+Sulphur200 (Homoeopathy Medicines ) weekly for 4-5 weeks.we have tried in stray dogs to eradicate skin fungus infections. tried on more than 2500 dogs.
drmkr
Ashwin Nambiar Drs, what systemic treatment do you use for Malassezia? Drugs other than ketoconazole?
Saurabh Saxena for chronic mixed skin infection wid itching ,alopecia generalised,i use liq gentian violet mix wid benzyl benzoate cream .before applying this ,i scrub whole body wid hard tooth brush and then apply this mixture.time consuming but very good results..use elizabetan collar or sedate it becoz it shd not be allowed to lick ..
Gautam Unny a very useful trick i use in stubborn chronic demodicosis is to mix amitraz 12.5% in liquid paraffin and apply locally. it has very good effects. i use 2 ml ridd in 30 ml of light pafaffin oil
Cyril Roy How true is the statement that ivermectin is resistance free?
In canada there is a big problem of dermatological problems in fish. Fish farming is a big industry in Canada to feed the big appettite of United States of America and also Canada itself. Most of the dematological problems are caused by sea lice, and also i think some kind of mange. Ivermectin has been regularly used to reduce this infection with good effect(population level eradication programs). But lately there has been severe reports of resistance.
I am writing this because, when i was doing some practice, i always thought ivermectin is resistance free. But now i am hearing that resistance is possible. Hope this is useful...
But we also have to understand that always population level treatment has the high risk of inducing resistance than individual animal treatment. So the risk may be low.
Swarupmay Majumdar Cypermetrin is not recommended in pups and dogs below 6 months. Avoid using CISAFLUX,Furfree,Softas in pups. This is s common tosee many vets prescribe Cisaflux in pups, it not safe and not recommended.
Swarupmay Majumdar Fipronil , Immidacloprid are well absorbed when there is natural oil on Skin. When we plan using Advantix,advantage or protector, it is better not to give bath atleast 7 days before and after applicatioins. See The results yourself.
Swarupmay Majumdar Cats are much more likely to respond to
antihistamines than dogs. However, administering oral medication on a
long-term basis may be challenging in this species.
Gautam Unny ivermectin is very safe if given at the righ dose. it does not cause any hepatic toxicity as commonly thought but instead is a potent neuro toxin in the high doses. there is no need to space ivermectin at weekly intervals.
it can be given daily at around 300micrograms/kg for as long a year for chronic mange. i have been using it at these dosages and have found no deleterious effects whatsoever.
to prevent drug resistance to ivermectin, please use it only where fully warrented and avoid using as a routine dewormer, thiough it is both a endo and ecto parasiticide
Swarupmay Majumdar Post: 1
Hierarchy of Skin antibiotics ( most effective to least effective) with dossage
* cephalexin 20-30mg?kg bid po
*Amoxy-clav 13.75mg/kg po bid
*Enrofloxacin 5mg/Kg sid po
*Chloramphenicol 5mg/kg po bid
*lincomycin 10-20mg/kg bid
*Trimethoprim-sulph 15-30mg bid ?
*clindamycin 10-20mg/kg bid po
efficacy of cephalexin is around 95%, Amoxy clav , enrofloxacin and Chloramphenicol around 75% ( all against s.intermidious). sulpha has variable results.
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